As blockchain adoption moves beyond speculation and into real-world applications, one of the biggest obstacles remains painfully simple: usability. Most users still face clunky onboarding, confusing wallets, and fragmented ecosystems.
Sam Barberie, Head of Strategy and Partnerships at Sequence, told CCN’s Dr. Guneet Kaur that fixing this isn’t just a UX challenge: it’s the key to mainstream crypto adoption.
“We’re solving two major problems in blockchain,” Barberie told CCN. “Wallet fragmentation and chain and token fragmentation.”
Sequence, a modular Web3 infrastructure platform, positions itself at the point where users actually use crypto, not just hold it. Barberie describes its mission as making digital ownership, payments, and interactions as seamless as logging into Google or paying with Apple Pay.
Bridging Fragmented Liquidity: How Sequence Simplifies Cross-Chain Payments
Historically, crypto developers faced a difficult trade-off: use traditional wallets like MetaMask for cross-app compatibility, or choose embedded wallets for smoother onboarding but limited portability.
“That created fragmentation, not just of user identity but of spending power,” Barberie said.
At the same time, the rise of multiple blockchains and stablecoins has splintered liquidity.
“There’s a lot of spending power in aggregate, but cross-chain payments remain very challenging,” he noted. Sequence’s solution is a one-click cross-chain payment system that allows users to pay with any token on any chain, while businesses receive settlement in the token of their choice.
This approach, Barberie believes, can “unlock the entire liquidity and spending power of the EVM ecosystem” while making Web3 payments feel instant and intuitive.
Building from the Ground Up: How Sequence Turns Modularity into Cohesion
Sequence’s modular infrastructure didn’t happen by accident. The company built it “bottoms up,” Barberie explained, starting from real-world needs in gaming, one of the toughest environments for end-to-end user experience design.
“Gaming involves everything from payments to trading,” he said. “Developers need to integrate for every component of that experience. That’s why modularity is crucial.”
However, modularity can sometimes lead to chaos if components don’t align. Barberie insists that Sequence’s design turns modularity into cohesion. “We solve fragmentation with modularity,” he said. “Each component works together like services on Google Cloud or AWS. Developers integrate what they need, but it all fits seamlessly.”
The platform’s flexibility allows builders to move quickly. According to Barberie, developers have launched fully functional NFT marketplaces “in as little as two minutes.”
Empowering Every Builder: From No-Code Creators to Enterprise Innovators
Barberie describes Sequence as a “choose-your-own-adventure” platform, powerful for enterprises, but accessible to non-technical creators.
Developers can use low-code or no-code tools to launch wallets, marketplaces, or payments instantly, while still having access to a full suite of SDKs and APIs for enterprise-grade scaling.
“That’s what’s exciting,” he said. “We can support quick go-to-market proof of concepts, but the technology is sophisticated enough for banks or major publishers to build whatever experience they want.”
This duality, ease for creators and depth for institutions, has made Sequence appealing to projects that want to move from idea to product without compromising on scalability or compliance.
Privacy, Compliance and Non-Custodial Architecture
With privacy becoming an increasingly central topic, especially as November marks “privacy month” across the industry, Barberie emphasizes that Sequence wallets are fully non-custodial.
“Neither we nor the developers ever have control over users’ assets,” he said. This not only empowers users with self-sovereignty but also aligns Sequence with global regulatory frameworks. Non-custodial models, he added, tend to receive “the most favorable view” from regulators because there’s no central point of custody.
Sequence also gives integrators flexibility. “Developers can determine how they want to handle user identity and privacy based on their markets,” he said.
“We simply provide the infrastructure.”
Abstracting Complexity: Enabling Fast, Gasless, Cross-Chain Transactions
One of Sequence’s most significant technical achievements is abstracting away the friction of multi-chain transactions. Its cross-chain transaction rails allow payments, swaps, and deposits to occur in under 20 seconds, completely gasless and non-custodial.
“Users can use any token on any chain to pay, regardless of what the recipient wants to receive,” Barberie explained.
“We just orchestrate the payment in a gasless, invisible way.”
In practice, this means a user with USDC on Polygon can pay a business that wants to settle in USDC on Base, all without needing to use a bridge or worry about fees. For developers, it opens new global payment flows without relying on centralized relayers or sacrificing user ownership.
Making Blockchain Invisible Through Seamless Abstraction Is the Key Goal
Looking ahead, Barberie believes the future of Web3 lies in abstraction, hiding blockchain complexity behind smooth, consumer-grade experiences.
“Even crypto natives don’t want friction,” he said. “Developers often end up building for small Web3-native audiences because of UX constraints. But mass adoption will come when blockchain feels invisible.”
In two years, Barberie predicts that crypto interactions, whether for payments, DeFi, or games, will be as simple as signing into an app. “Everything in Web3 will be opt-in and customizable. The experience will be the same whether you’re a beginner or an advanced user.”
For him, that’s the barometer of success: “When my parents can use it without me explaining how.”
Asked what piece of Sequence’s technology will still matter a decade from now, Barberie didn’t hesitate.
“The abstraction layer,” he said. “Once the EVM ecosystem operates as a unified whole, developers can focus on building great applications, and users won’t even realize there’s a blockchain underneath.”
The information provided in this article is for informational purposes only. It is not intended to be, nor should it be construed as, financial advice. We do not make any warranties regarding the completeness, reliability, or accuracy of this information. All investments involve risk, and past performance does not guarantee future results. We recommend consulting a financial advisor before making any investment decisions.
Giuseppe Ciccomascolo began his career as an investigative journalist in Italy, where he contributed to both local and national newspapers, focusing on various financial sectors.
Upon relocating to London, he worked as an analyst for Fitch's CapitalStructure and later as a Senior Reporter for Alliance News. In 2017, Giuseppe transitioned to covering cryptocurrency-related news, producing documentaries and articles on Bitcoin and other emerging digital currencies. He also played a pivotal role in establishing the academy for a cryptocurrency exchange website. Crypto remained his primary area of interest throughout his tenure as a writer for ThirdFloor.
Dr. Guneet Kaur is a senior editor at CCN.com and a Science Fellow at Exponential Science. She is a fintech and blockchain expert with extensive experience in digital finance education, blockchain ecosystems, and cryptocurrency markets. She has worked with global media such as Cointelegraph, as well as education and blockchain platforms, to design and lead strategic content and learning initiatives. As an educator and assessor for top-tier executive programs, she bridges real-world fintech trends with academic insight.
Dr. Kaur is also a published researcher and peer reviewer across fintech and data science journals, including Financial Innovation Journal and International Journal of Big Data Intelligence and Applications. Her work spans data-driven analysis, Web3 innovation, and technical content development. With a strong foundation in both industry and academia, she translates complex financial technologies into practical applications, empowering learners, professionals, and institutions across the rapidly evolving digital finance landscape.
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