Semler Scientific Bets Big on Bitcoin With 105K BTC Target—Even as Strategy Wobbles

Key Takeaways

• Semler Scientific plans to accumulate over 100,000 BTC by the end of 2027.
• The company has named a new Director of Bitcoin Strategy to lead the effort.
• Semler adopted a Bitcoin treasury in May 2024 and currently holds 4,449 BTC.

Semler Scientific is going all in on Bitcoin.

The Nasdaq-listed healthcare tech firm has unveiled an aggressive plan to scale its Bitcoin treasury to over 100,000 BTC by the end of 2027, mirroring Strategy’s (formerly MicroStrategy) bold accumulation strategy.

Semler, which adopted Bitcoin as its primary treasury reserve asset in May 2024, says it has already achieved a 287% yield on its BTC holdings and intends to double down.

Semler Scientific Targets 100,000 BTC Stack

In a recent press release , Semler laid out a roadmap to grow its Bitcoin reserves significantly over the next few years. The company plans to hold:

•  10,000 BTC by the end of 2025.
• 42,000 BTC by the end of 2026.
• 105,000 BTC by the end of 2027.

These purchases will be funded through a mix of equity and debt raises, as well as operational cash flow.

So far, Semler has amassed 4,449 BTC, worth roughly $446 million at current market prices.

Chairman Eric Semler said the pivot to Bitcoin has already delivered outsized results:

“Since adopting the Bitcoin Standard, we’ve achieved approximately 287% BTC yield and a $177 million gain through June 3, 2025. With a strong team and deepening connections in the Bitcoin community, we’re ready to accelerate our strategy.”

To support this push, the company has tapped Joe Burnett as its new Director of Bitcoin Strategy. Burnett, a respected voice in the Bitcoin space, previously worked as Director of Market Research at Unchained and has spent over seven years promoting Bitcoin as a sound money alternative.

BTC on Balance Sheets: A Growing Trend

Semler’s Bitcoin strategy is part of a broader corporate movement.

According to data from Bitcoin Treasuries , 235 public and private entities now hold a combined 3.45 million BTC on their balance sheets.

Nearly 100 of those are publicly traded.

Strategy first wrote the playbook in 2020, and despite severe price drawdowns during the 2021–22 bear market, the company stayed the course and bought even more.

Founder Michael Saylor, once a Bitcoin skeptic, is now one of its loudest evangelists, calling on firms like Tesla and SpaceX to follow suit.

Today, the corporate race for Bitcoin is heating up, with many companies issuing debt or equity securities specifically to fund BTC acquisitions.

Semler Scientific may be the latest to join—but it’s clearly aiming to be one of the largest.